This work is licensed under a Creative Commons Attribution 4.0 International License.
Aurein-5.2
General Information
DCTPep ID DCTPep04670
Peptide Name Aurein-5.2
Sequence GLMSSIGKALGGLIVDVLKPKTPAS
Sequence Length 25
UniProt ID P82402 P69031 P69030
PubChem CID Not available
Origin Litoria aurea
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C110H194N28O32S1
Absent amino acids CEFHNQRWY
Theoretical pI 9.70
Acidic residues 1
Basic residues 3
Polar residues 8
Molecular weight (Average) 2452.98
Molecular weight (Monoisotopic) 2451.41
Common amino acids GL
Net charge 2
Instability index (II) 28.3
Aliphatic index 124.80
Grand average of hydropathicity (GRAVY) 0.600
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 15203252
Title Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance
Doi 10.1016/j.peptides.2004.03.006
Year 2004
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DRAMP ID DRAMP01620
This work is licensed under a Creative Commons Attribution 4.0 International License.