This work is licensed under a Creative Commons Attribution 4.0 International License.
Caerin 1.9
General Information
DCTPep ID DCTPep04679
Peptide Name Caerin 1.9
Sequence GLFGVLGSIAKHVLPHVVPVIAEKL
Sequence Length 25
UniProt ID P81252
PubChem CID Not available
Origin Litoria splendida
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Amidation
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C124H205N31O29
Absent amino acids CDMNQRTWY
Theoretical pI 8.61
Acidic residues 1
Basic residues 4
Polar residues 4
Molecular weight (Average) 2594.18
Molecular weight (Monoisotopic) 2592.55
Common amino acids V
Net charge 3
Instability index (II) 29.32
Aliphatic index 159.60
Grand average of hydropathicity (GRAVY) 1.148
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 15203252
Title Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance
Doi 10.1016/j.peptides.2004.03.006
Year 2004
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.