Human lactoferricin
General Information
DCTPep ID DCTPep04682
Peptide Name Human lactoferricin
Sequence GRRRRSVQWCAVSQPEATKCFQWQRNMRKVRGPPVSCIKRDSPIQCIQA
Sequence Length 49
UniProt ID P02788
PubChem CID Not available
Origin Arabidopsis thaliana
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Amidation
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C244H403N85O66S5
Absent amino acids HLY
Theoretical pI 11.24
Acidic residues 2
Basic residues 11
Polar residues 12
Molecular weight (Average) 5743.71
Molecular weight (Monoisotopic) 5739.94
Common amino acids R
Net charge 9
Instability index (II) 93.55
Aliphatic index 53.67
Grand average of hydropathicity (GRAVY) -0.851
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 11250
Abs 0.1% (=1 g/l) 1.959, assuming all pairs of Cys residues form cystines
Ext. coefficient 11000
Abs 0.1% (=1 g/l) 1.915, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24703967
Title Not available
Doi Not available
Year Not available
Literature 2
Pubmed ID 17481742
Title Not available
Doi Not available
Year Not available
Literature 3
Pubmed ID 16048952
Title Not available
Doi Not available
Year Not available
Literature 4
Pubmed ID 11254635
Title Not available
Doi Not available
Year Not available
Literature 5
Pubmed ID 10066056
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8171