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Lfcin B (17-31)
General Information
DCTPep ID DCTPep04689
Peptide Name Lfcin B (17-31)
Sequence FKCRRWQWRMKKLGA
Sequence Length 15
UniProt ID P24627
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Acetylation
Other Modification None
Chiral L
Physicochemical Information
Formula C91H144N30O17S2
Absent amino acids DEHINPSTVY
Theoretical pI 11.74
Acidic residues 0
Basic residues 6
Polar residues 2
Molecular weight (Average) 1994.46
Molecular weight (Monoisotopic) 1993.08
Common amino acids KR
Net charge 6
Instability index (II) 64.37
Aliphatic index 32.67
Grand average of hydropathicity (GRAVY) -1.207
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 11000
Abs 0.1% (=1 g/l) 5.515, assuming all pairs of Cys residues form cystines
Ext. coefficient 11000
Abs 0.1% (=1 g/l) 5.515, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 16572423
Title The antimicrobial peptide, lactoferricin B, is cytotoxic to neuroblastoma cells in vitro and inhibits xenograft growth in vivo
Year 2006
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
This work is licensed under a Creative Commons Attribution 4.0 International License.