Brevinin-1BLb
General Information
DCTPep ID DCTPep04690
Peptide Name Brevinin-1BLb
Sequence FLPIIAGVAAKVLPKIFCAISKKC
Sequence Length 24
UniProt ID Not available
PubChem CID Not available
Origin Lithobates blairi
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Cys18<--->Cys24
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C121H204N28O26S2
Absent amino acids DEHMNQRTWY
Theoretical pI 9.70
Acidic residues 0
Basic residues 4
Polar residues 4
Molecular weight (Average) 2531.24
Molecular weight (Monoisotopic) 2529.49
Common amino acids AIK
Net charge 4
Instability index (II) 18.56
Aliphatic index 138.33
Grand average of hydropathicity (GRAVY) 1.325
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 125
Abs 0.1% (=1 g/l) 0.049, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 19254736
Title Not available
Doi Not available
Year Not available
Literature 2
Pubmed ID 18957441
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
CancerPPD ID 4360