Brevinin-1BLb

General Information


DCTPep ID  DCTPep04690

Peptide Name   Brevinin-1BLb

Sequence  FLPIIAGVAAKVLPKIFCAISKKC

Sequence Length  24

UniProt ID  Not available

PubChem CID  Not available

Origin  Lithobates blairi

Type  Native peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Cyclic

Disulfide/Other Bond  Cys18<--->Cys24

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C121H204N28O26S2

Absent amino acids  DEHMNQRTWY

Theoretical pI  9.70

Acidic residues  0

Basic residues  4

Polar residues  4

Molecular weight (Average)  2531.24

Molecular weight (Monoisotopic)  2529.49

Common amino acids  AIK

Net charge  4

Instability index (II)  18.56

Aliphatic index  138.33

Grand average of hydropathicity (GRAVY)  1.325

Half Life 
  1.1 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 125
  Abs 0.1% (=1 g/l) 0.049, assuming all pairs of Cys residues form cystines
  Ext. coefficient 0
  Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 19254736

Title  Not available

Doi Not available

Year  Not available

Literature 2

Pubmed ID 18957441

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




CancerPPD ID  4360

DCTPep is developed by Dr.Zheng's team.