This work is licensed under a Creative Commons Attribution 4.0 International License.
Maculatin 1.3
General Information
DCTPep ID DCTPep04692
Peptide Name Maculatin 1.3
Sequence GLLGLLGSVVSHVVPAIVGHF
Sequence Length 21
UniProt ID P82066
PubChem CID 49777295
Origin Litoria eucnemis
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C98H159N25O24
Absent amino acids CDEKMNQRTWY
Theoretical pI 6.92
Acidic residues 0
Basic residues 2
Polar residues 6
Molecular weight (Average) 2071.49
Molecular weight (Monoisotopic) 2070.2
Common amino acids V
Net charge 2
Instability index (II) 14.84
Aliphatic index 166.67
Grand average of hydropathicity (GRAVY) 1.624
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 27246787
Title Inhibition of methicillin-resistant Staphylococcus aureus (MRSA) by antimicrobial peptides (AMPs) and plant essential oils
Doi 10.1080/13880209.2016.1190763
Year 2016
Literature 2
Pubmed ID 22771617
Title Host-defense peptides of Australian anurans. Part 2. Structure, activity, mechanism of action, and evolutionary significance
Doi 10.1016/j.peptides.2012.06.017
Year 2012
Literature 3
Pubmed ID 22445495
Title Not available
Doi Not available
Year Not available
Literature 4
Pubmed ID 20086159
Title Not available
Doi Not available
Year Not available
Literature 5
Pubmed ID 18957441
Title Not available
Doi Not available
Year Not available
Literature 6
Pubmed ID 15203252
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
This work is licensed under a Creative Commons Attribution 4.0 International License.