Nisin Z

General Information


DCTPep ID  DCTPep04695

Peptide Name   Nisin Z

Sequence  ITSISLCTPGCKTGALMGCNMKTATCNCSIHVSK

Sequence Length  34

UniProt ID  LANZ_LACLL  P29559 

PubChem CID  Not available

Origin  Lactococcus lactis

Type  Native peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  1WCO 

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Not available

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C141H245N41O46S7

Absent amino acids  DEFQRWY

Theoretical pI  8.78

Acidic residues  0

Basic residues  4

Polar residues  19

Molecular weight (Average)  3475.16

Molecular weight (Monoisotopic)  3472.61

Common amino acids  CT

Net charge  4

Instability index (II)  17.08

Aliphatic index  71.76

Grand average of hydropathicity (GRAVY)  0.406

Half Life 
  20 hours (mammalian reticulocytes, in vitro).
  30 min (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 250
  Abs 0.1% (=1 g/l) 0.072, assuming all pairs of Cys residues form cystines
  Ext. coefficient 0
  Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 8439149

Title  Not available

Doi Not available

Year  Not available

Literature 2

Pubmed ID 7626780

Title  Not available

Doi Not available

Year  Not available

Literature 3

Pubmed ID 1935953

Title  Not available

Doi Not available

Year  Not available

Literature 4

Pubmed ID 15361862

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRAMP ID  DRAMP00037

DCTPep is developed by Dr.Zheng's team.