This work is licensed under a Creative Commons Attribution 4.0 International License.
Cypemycin (Bacteriocin)
General Information
DCTPep ID DCTPep04697
Peptide Name Cypemycin (Bacteriocin)
Sequence ATPATPTVAQFVIQGSTICLVC
Sequence Length 22
UniProt ID E5KIB6
PubChem CID Not available
Origin Streptomyces
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C98H162N24O30S2
Absent amino acids DEHKMNRWY
Theoretical pI 5.55
Acidic residues 0
Basic residues 0
Polar residues 8
Molecular weight (Average) 2220.63
Molecular weight (Monoisotopic) 2219.13
Common amino acids T
Net charge 0
Instability index (II) 23.63
Aliphatic index 106.36
Grand average of hydropathicity (GRAVY) 1.109
Half Life
4.4 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 125
Abs 0.1% (=1 g/l) 0.056, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 7802859
Title Not available
Doi Not available
Year Not available
Literature 2
Pubmed ID 20805503
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DRAMP ID DRAMP00232
This work is licensed under a Creative Commons Attribution 4.0 International License.