This work is licensed under a Creative Commons Attribution 4.0 International License.
Dermaseptin-B3
General Information
DCTPep ID DCTPep04706
Peptide Name Dermaseptin-B3
Sequence ALWKNMLKGIGKLAGQAALGAVKTLVGAE
Sequence Length 29
UniProt ID P81485
PubChem CID Not available
Origin Phyllomedusa bicolor
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C132H226N36O35S1
Absent amino acids CDFHPRSY
Theoretical pI 10.00
Acidic residues 1
Basic residues 4
Polar residues 7
Molecular weight (Average) 2909.53
Molecular weight (Monoisotopic) 2907.67
Common amino acids A
Net charge 3
Instability index (II) -6.59
Aliphatic index 121.38
Grand average of hydropathicity (GRAVY) 0.514
Half Life
4.4 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 1.890
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 9614066
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.