DCTPep ID  DCTPep04710

Peptide Name   Varv peptide C (Varv C; Plant defensin)

Sequence  GVPICGETCVGGTCNTPGCSCSWPVCTRN

Sequence Length  29

UniProt ID  P58448 

PubChem CID  Not available

Origin  Oldenlandia affinis

Type  Native peptide

Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

PDB ID  1NB1 

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Cyclic

Disulfide/Other Bond  Cys5<--->Cys19; Cys9<--->Cys21; Cys14<--->Cys26; NCB: Gly1<--->Asn29

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L

Grand average of hydropathicity (GRAVY)  0.172

Half Life 
  30 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 5875
  Abs 0.1% (=1 g/l) 2.024, assuming all pairs of Cys residues form cystines
  Ext. coefficient 5500
  Abs 0.1% (=1 g/l) 1.895, assuming all Cys residues are reduced

Amino acid distribution

Literature 1

Pubmed ID 26399495

Title  Not available

Doi Not available

Year  Not available

Literature 2

Pubmed ID 21413917

Title  Not available

Doi Not available

Year  Not available

Literature 3

Pubmed ID 10075760

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available

DRAMP ID  DRAMP00786