This work is licensed under a Creative Commons Attribution 4.0 International License.
Aurein-2.4
General Information
DCTPep ID DCTPep04715
Peptide Name Aurein-2.4
Sequence GLFDIVKKVVGTIAGL
Sequence Length 16
UniProt ID P82391
PubChem CID Not available
Origin Litoria aurea
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C77H132N18O20
Absent amino acids CEHMNPQRSWY
Theoretical pI 8.59
Acidic residues 1
Basic residues 2
Polar residues 4
Molecular weight (Average) 1630
Molecular weight (Monoisotopic) 1628.99
Common amino acids GV
Net charge 1
Instability index (II) -5.94
Aliphatic index 158.12
Grand average of hydropathicity (GRAVY) 1.288
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 15203252
Title Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance
Doi 10.1016/j.peptides.2004.03.006
Year 2004
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 8528
This work is licensed under a Creative Commons Attribution 4.0 International License.