Peptide Libraray

Viscotoxin A1

General Information

DCTPep ID DCTPep04718

Peptide Name Viscotoxin A1

Sequence KSCCPNTTGRNIYNTCRLTGSSRETCAKLSGCKIISASTCPSNYPK

Sequence Length 46

UniProt ID D0VWT3

PubChem CID Not available

Origin Viscum album

Type Native peptide

Classification

Cancer therapy related peptides

Activity Information

Hemolytic Activity Not available

Normal (non-cancerous) Cytotoxicity Not available

Target Not available

Affinity Not available

Mechanism Not available

Structure Information

PDB ID 3C8P

Predicted Structure Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity Not available

Linear/Cyclic Not available

Disulfide/Other Bond Not available

N-terminal Modification Free

C-terminal Modification Free

Other Modification None

Chiral L

Physicochemical Information

Formula C201H337N63O68S6

Absent amino acids DFHMQVW

Theoretical pI 9.30

Acidic residues 1

Basic residues 7

Polar residues 28

Molecular weight (Average) 4916.63

Molecular weight (Monoisotopic) 4913.32

Common amino acids S

Net charge 6

Instability index (II) 41.65

Aliphatic index 46.74

Grand average of hydropathicity (GRAVY) -0.550

Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).

Extinction coefficients
Ext. coefficient 3355
Abs 0.1% (=1 g/l) 0.682, assuming all pairs of Cys residues form cystines
Ext. coefficient 2980
Abs 0.1% (=1 g/l) 0.606, assuming all Cys residues are reduced

Amino acid distribution

Literature Information

Literature 1

Pubmed ID 9348108

Title Not available

Doi Not available

Year Not available

Literature 2

Pubmed ID 18957441

Title Not available

Doi Not available

Year Not available

Literature 3

Pubmed ID 18703848

Title Not available

Doi Not available

Year Not available

Patent

Patent ID Not available

Patent Title Not available

Other Iinformation Not available

Other Published ID Not available

External Code

DRAMP ID DRAMP00952

CancerPPD ID 4443