Curcuma longa (Turmeric) (Curcuma domestica)

General Information


DCTPep ID  DCTPep04719

Peptide Name   Curcuma longa (Turmeric) (Curcuma domestica)

Sequence  LCPLDVLQLSSELLDIDGNEVEASRILSDITAFGGIRCPLTVVQSRGIGTIISSPYRFIAEGHPLSLKDMDGWFRVSDDEFNNYK

Sequence Length  85

UniProt ID  P85278 

PubChem CID  Not available

Origin  Curcuma longa

Type  Native peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  2L3I 

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Not available

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C418H658N110O131S3

Absent amino acids  Not Applicable

Theoretical pI  4.43

Acidic residues  13

Basic residues  8

Polar residues  26

Molecular weight (Average)  9416.66

Molecular weight (Monoisotopic)  9410.74

Common amino acids  LS

Net charge  -5

Instability index (II)  36.77

Aliphatic index  103.18

Grand average of hydropathicity (GRAVY)  0.000

Half Life 
  5.5 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 8605
  Abs 0.1% (=1 g/l) 0.914, assuming all pairs of Cys residues form cystines
  Ext. coefficient 8480
  Abs 0.1% (=1 g/l) 0.901, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 18177267

Title  New biological activity against phospholipase A2 by Turmerin, a protein from Curcuma longa L

Doi 10.1515/BC.2008.024

Year  2008

Literature 2

Pubmed ID 1731625

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DRAMP ID  DRAMP02472

DCTPep is developed by Dr.Zheng's team.