Kalata B1

General Information


DCTPep ID  DCTPep04723

Peptide Name   Kalata B1

Sequence  CGETCVGGTCNTPGCTCSWPVCTRNGLPV

Sequence Length  29

UniProt ID  P56254 

PubChem CID  Not available

Origin  Oldenlandia affinis

Type  Native peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  1ZNU  2JUE  1NB1 

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Not available

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C117H187N35O40S6

Absent amino acids  ADFHIKMQY

Theoretical pI  5.96

Acidic residues  1

Basic residues  1

Polar residues  19

Molecular weight (Average)  2916.34

Molecular weight (Monoisotopic)  2914.2

Common amino acids  C

Net charge  0

Instability index (II)  41.41

Aliphatic index  43.45

Grand average of hydropathicity (GRAVY)  0.152

Half Life 
  1.2 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 5875
  Abs 0.1% (=1 g/l) 2.015, assuming all pairs of Cys residues form cystines
  Ext. coefficient 5500
  Abs 0.1% (=1 g/l) 1.886, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 23468118

Title  Not available

Doi Not available

Year  Not available

Literature 2

Pubmed ID 21928440

Title  Not available

Doi Not available

Year  Not available

Literature 3

Pubmed ID 16817894

Title  Not available

Doi Not available

Year  Not available

Literature 4

Pubmed ID 12482868

Title  Not available

Doi Not available

Year  Not available

Literature 5

Pubmed ID 10747913

Title  Not available

Doi Not available

Year  Not available

Literature 6

Pubmed ID 10441158

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DCTPep is developed by Dr.Zheng's team.