This work is licensed under a Creative Commons Attribution 4.0 International License.
Aurein-2.4.1
General Information
DCTPep ID DCTPep04724
Peptide Name Aurein-2.4.1
Sequence FDIVKKVVGTIAGL
Sequence Length 14
UniProt ID P82391
PubChem CID Not available
Origin Litoria aurea
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C69H118N16O18
Absent amino acids CEHMNPQRSWY
Theoretical pI 8.59
Acidic residues 1
Basic residues 2
Polar residues 3
Molecular weight (Average) 1459.79
Molecular weight (Monoisotopic) 1458.88
Common amino acids V
Net charge 1
Instability index (II) -8.21
Aliphatic index 152.86
Grand average of hydropathicity (GRAVY) 1.229
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 10951191
Title The antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2
Doi 10.1046/j.1432-1327.2000.01536.x
Year 2000
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.