This work is licensed under a Creative Commons Attribution 4.0 International License.
Viscotoxin B2
General Information
DCTPep ID DCTPep04730
Peptide Name Viscotoxin B2
Sequence KSCCKNTTGRNIYNTCRFAGGSRERCAKLSGCKIISASTCPSDYPK
Sequence Length 46
UniProt ID Not available
PubChem CID Not available
Origin Viscum album
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID 1ORL
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Cys8<--->Cys25; Cys17<--->Cys27
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C205H340N66O66S6
Absent amino acids HMQVW
Theoretical pI 9.46
Acidic residues 2
Basic residues 9
Polar residues 25
Molecular weight (Average) 4977.72
Molecular weight (Monoisotopic) 4974.36
Common amino acids CS
Net charge 7
Instability index (II) 37.8
Aliphatic index 40.43
Grand average of hydropathicity (GRAVY) -0.641
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 3355
Abs 0.1% (=1 g/l) 0.674, assuming all pairs of Cys residues form cystines
Ext. coefficient 2980
Abs 0.1% (=1 g/l) 0.599, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 18957441
Title Not available
Doi Not available
Year Not available
Literature 2
Pubmed ID 15700822
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
CancerPPD ID 4440
This work is licensed under a Creative Commons Attribution 4.0 International License.