Viscotoxin A2

General Information


DCTPep ID  DCTPep04732

Peptide Name   Viscotoxin A2

Sequence  KSCCPNTTGRNIYNTCRFGGGSRQVCASLSGCKIISASTCPSDYPK

Sequence Length  46

UniProt ID  Not available

PubChem CID  Not available

Origin  Viscum album

Type  Native peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  1JMN 

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Not available

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C199H324N62O66S6

Absent amino acids  EHMW

Theoretical pI  9.13

Acidic residues  1

Basic residues  6

Polar residues  27

Molecular weight (Average)  4833.5

Molecular weight (Monoisotopic)  4830.22

Common amino acids  S

Net charge  5

Instability index (II)  49.07

Aliphatic index  44.57

Grand average of hydropathicity (GRAVY)  -0.383

Half Life 
  1.3 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  3 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 3355
  Abs 0.1% (=1 g/l) 0.694, assuming all pairs of Cys residues form cystines
  Ext. coefficient 2980
  Abs 0.1% (=1 g/l) 0.617, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 9348108

Title  Not available

Doi Not available

Year  Not available

Literature 2

Pubmed ID 18957441

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




CancerPPD ID  4445

DCTPep is developed by Dr.Zheng's team.