This work is licensed under a Creative Commons Attribution 4.0 International License.
TAT(48-57)
General Information
DCTPep ID DCTPep04734
Peptide Name TAT(48-57)
Sequence GRKKRRQRRR
Sequence Length 10
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C55H109N31O12
Absent amino acids ACDEFHILMNPSTVWY
Theoretical pI 12.70
Acidic residues 0
Basic residues 8
Polar residues 1
Molecular weight (Average) 1396.67
Molecular weight (Monoisotopic) 1395.89
Common amino acids R
Net charge 8
Instability index (II) 232.7
Aliphatic index 0.00
Grand average of hydropathicity (GRAVY) -3.870
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22319541
Title Infection by CXCR4-Tropic Human Immunodeficiency Virus Type 1 Is Inhibited by the Cationic Cell-Penetrating Peptide Derived from HIV-1 Tat
Year 2012
Literature 2
Pubmed ID 15467750
Title A RasGAP-derived cell permeable peptide potently enhances genotoxin-induced cytotoxicity in tumor cells
Year 2004
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
This work is licensed under a Creative Commons Attribution 4.0 International License.