This work is licensed under a Creative Commons Attribution 4.0 International License.
50S ribosomal protein L1 HP(2-20) [D18W]
General Information
DCTPep ID DCTPep04739
Peptide Name 50S ribosomal protein L1 HP(2-20) [D18W]
Sequence AKKVFKRLEKLFSKIQNWK
Sequence Length 19
UniProt ID P56029
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID 1P0J
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C114H187N31O25
Absent amino acids CDGHMPTY
Theoretical pI 10.68
Acidic residues 1
Basic residues 7
Polar residues 2
Molecular weight (Average) 2391.93
Molecular weight (Monoisotopic) 2390.43
Common amino acids K
Net charge 6
Instability index (II) -0.14
Aliphatic index 82.11
Grand average of hydropathicity (GRAVY) -0.863
Half Life
4.4 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 2.299
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 17961502
Title Amphipathic alpha-helical peptide, HP (2-20), and its analogues derived from Helicobacter pylori: pore formation mechanism in various lipid compositions
Doi 10.1016/j.bbamem.2007.09.020
Year 2008
Literature 2
Pubmed ID 16255716
Title Not available
Doi Not available
Year Not available
Literature 3
Pubmed ID 12147359
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DRAMP ID DRAMP04076
DBAASP ID 892
This work is licensed under a Creative Commons Attribution 4.0 International License.