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P5
General Information
DCTPep ID DCTPep04770
Peptide Name P5
Sequence KWKKLLKKPLLKKLLKKL
Sequence Length 18
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Acetylation
Other Modification None
Chiral L
Physicochemical Information
Formula C112H204N28O19
Absent amino acids ACDEFGHIMNQRSTVY
Theoretical pI 10.90
Acidic residues 0
Basic residues 9
Polar residues 0
Molecular weight (Average) 2247.03
Molecular weight (Monoisotopic) 2245.59
Common amino acids K
Net charge 9
Instability index (II) -23.04
Aliphatic index 151.67
Grand average of hydropathicity (GRAVY) -0.611
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 2.448
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 14514057
Title Antibiotic activity of Leu-Lys rich model peptides
Year 2003
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 6494
This work is licensed under a Creative Commons Attribution 4.0 International License.