General Information


DCTPep ID  DCTPep04771

Peptide Name  

Sequence  KWKLKPLLKKLLKKL

Sequence Length  15

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C94H169N23O16

Absent amino acids  ACDEFGHIMNQRSTVY

Theoretical pI  10.78

Acidic residues  0

Basic residues  7

Polar residues  0

Molecular weight (Average)  1877.52

Molecular weight (Monoisotopic)  1876.31

Common amino acids  K

Net charge  7

Instability index (II)  -29.65

Aliphatic index  156.00

Grand average of hydropathicity (GRAVY)  -0.467

Half Life 
  1.3 hours (mammalian reticulocytes, in vitro).
  3 min (yeast, in vivo).
  3 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 5500
  Abs 0.1% (=1 g/l) 2.929

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 14514057

Title  Antibiotic activity of Leu-Lys rich model peptides

Doi 10.1023/a:1024995105208

Year  2003

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  5210

DCTPep is developed by Dr.Zheng's team.