L-amino-acid oxidase
General Information
DCTPep ID DCTPep04777
Peptide Name L-amino-acid oxidase
Sequence ADDKNPLEECFRETDYEEFLEIARNGLKATSNPKRVV
Sequence Length 37
UniProt ID P0DI88
PubChem CID Not available
Origin Bothrops jararaca
Type Native peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C186H294N52O63S1
Absent amino acids HMQW
Theoretical pI 4.65
Acidic residues 9
Basic residues 6
Polar residues 9
Molecular weight (Average) 4298.75
Molecular weight (Monoisotopic) 4296.11
Common amino acids E
Net charge -3
Instability index (II) 42.04
Aliphatic index 65.95
Grand average of hydropathicity (GRAVY) -0.986
Half Life
4.4 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.347, assuming all pairs of Cys residues form cystines
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.347, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 20615423
Title Not available
Doi Not available
Year Not available
Literature 2
Pubmed ID 19101583
Title Not available
Doi Not available
Year Not available
Literature 3
Pubmed ID 18346051
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DRAMP ID DRAMP02459