This work is licensed under a Creative Commons Attribution 4.0 International License.
Dermaseptin-PH
General Information
DCTPep ID DCTPep04779
Peptide Name Dermaseptin-PH
Sequence ALWKEVLKNAGKAALNEINNLV
Sequence Length 22
UniProt ID Not available
PubChem CID Not available
Origin
Type
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Not available
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C109H182N30O31
Absent amino acids CDFHMPQRSTY
Theoretical pI 8.54
Acidic residues 2
Basic residues 3
Polar residues 5
Molecular weight (Average) 2408.83
Molecular weight (Monoisotopic) 2407.36
Common amino acids ALN
Net charge 1
Instability index (II) 21.35
Aliphatic index 133.18
Grand average of hydropathicity (GRAVY) 0.059
Half Life
4.4 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 2.283
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 29064402
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.