General Information


DCTPep ID  DCTPep04781

Peptide Name  

Sequence  CGETCTLGTCYTAGCSCSWPVCTRNGVPI

Sequence Length  29

UniProt ID  P58451 

PubChem CID  Not available

Origin 

Type 

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  3E4H 

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Cyclic

Disulfide/Other Bond  Cys1<--->Cys15; Cys5<--->Cys17; Cys10<--->Cys22

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C122H192N34O41S6

Absent amino acids  DFHKMQ

Theoretical pI  5.96

Acidic residues  1

Basic residues  1

Polar residues  19

Molecular weight (Average)  2983.43

Molecular weight (Monoisotopic)  2981.23

Common amino acids  C

Net charge  0

Instability index (II)  47.28

Aliphatic index  50.34

Grand average of hydropathicity (GRAVY)  0.341

Half Life 
  1.2 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 7365
  Abs 0.1% (=1 g/l) 2.469, assuming all pairs of Cys residues form cystines
  Ext. coefficient 6990
  Abs 0.1% (=1 g/l) 2.343, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 19211551

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DCTPep is developed by Dr.Zheng's team.