This work is licensed under a Creative Commons Attribution 4.0 International License.
General Information
DCTPep ID DCTPep04781
Peptide Name
Sequence CGETCTLGTCYTAGCSCSWPVCTRNGVPI
Sequence Length 29
UniProt ID P58451
PubChem CID Not available
Origin
Type
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID 3E4H
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Cys1<--->Cys15; Cys5<--->Cys17; Cys10<--->Cys22
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C122H192N34O41S6
Absent amino acids DFHKMQ
Theoretical pI 5.96
Acidic residues 1
Basic residues 1
Polar residues 19
Molecular weight (Average) 2983.43
Molecular weight (Monoisotopic) 2981.23
Common amino acids C
Net charge 0
Instability index (II) 47.28
Aliphatic index 50.34
Grand average of hydropathicity (GRAVY) 0.341
Half Life
1.2 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 7365
Abs 0.1% (=1 g/l) 2.469, assuming all pairs of Cys residues form cystines
Ext. coefficient 6990
Abs 0.1% (=1 g/l) 2.343, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 19211551
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.