(HHPHG)2

General Information


DCTPep ID  DCTPep04793

Peptide Name   (HHPHG)2

Sequence  HHPHGHHPHG

Sequence Length  10

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Acetylation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C50H64N22O11

Absent amino acids  ACDEFIKLMNQRSTVWY

Theoretical pI  7.21

Acidic residues  0

Basic residues  6

Polar residues  2

Molecular weight (Average)  1149.2

Molecular weight (Monoisotopic)  1148.51

Common amino acids  H

Net charge  6

Instability index (II)  -17.5

Aliphatic index  0.00

Grand average of hydropathicity (GRAVY)  -2.320

Half Life 
  3.5 hours (mammalian reticulocytes, in vitro).
  10 min (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 15313924

Title  Peptides derived from the histidine-proline domain of the histidine-proline-rich glycoprotein bind to tropomyosin and have antiangiogenic and antitumor activities

Doi 10.1158/0008-5472.CAN-04-0440

Year  2004

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




CancerPPD ID  4185

CancerPPD ID  4186

DCTPep is developed by Dr.Zheng's team.