This work is licensed under a Creative Commons Attribution 4.0 International License.
Cyclic [W(RW)4 ]-Dox
General Information
DCTPep ID DCTPep04809
Peptide Name Cyclic [W(RW)4 ]-Dox
Sequence WRWRWRWRW
Sequence Length 9
UniProt ID Not available
PubChem CID Not available
Origin
Type
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond NCB: Trp1<--->Trp9
N-terminal Modification Free
C-terminal Modification Dox, Doxorubicin
Other Modification None
Chiral L
Physicochemical Information
Formula C79H100N26O10
Absent amino acids ACDEFGHIKLMNPQSTVY
Theoretical pI 12.48
Acidic residues 0
Basic residues 4
Polar residues 0
Molecular weight (Average) 1573.83
Molecular weight (Monoisotopic) 1572.81
Common amino acids W
Net charge 4
Instability index (II) 263.47
Aliphatic index 0.00
Grand average of hydropathicity (GRAVY) -2.500
Half Life
2.8 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 27500
Abs 0.1% (=1 g/l) 17.473
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23301519
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
This work is licensed under a Creative Commons Attribution 4.0 International License.