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FSEC
General Information
DCTPep ID DCTPep04827
Peptide Name FSEC
Sequence CELDENNTPMC
Sequence Length 11
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C48H77N13O21S3
Absent amino acids AFGHIKQRSVWY
Theoretical pI 3.57
Acidic residues 3
Basic residues 0
Polar residues 5
Molecular weight (Average) 1268.39
Molecular weight (Monoisotopic) 1267.45
Common amino acids CEN
Net charge -3
Instability index (II) -5.48
Aliphatic index 35.45
Grand average of hydropathicity (GRAVY) -0.827
Half Life
1.2 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 125
Abs 0.1% (=1 g/l) 0.099, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 11311231
Title A small peptide derived from Flt-1 (VEGFR-1) functions as an angiogenic inhibitor
Doi 10.1016/s0014-5793(01)02314-6
Year 2001
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.