aa 146-167; loop-5

General Information


DCTPep ID  DCTPep04838

Peptide Name   aa 146-167; loop-5

Sequence  CLWMDWVTEKNINGHQAKFFAC

Sequence Length  22

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Cyclic

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C120H173N31O31S3

Absent amino acids  PRSY

Theoretical pI  6.73

Acidic residues  2

Basic residues  3

Polar residues  6

Molecular weight (Average)  2642.06

Molecular weight (Monoisotopic)  2640.21

Common amino acids  ACFKNW

Net charge  1

Instability index (II)  73.98

Aliphatic index  57.73

Grand average of hydropathicity (GRAVY)  -0.127

Half Life 
  1.2 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 11125
  Abs 0.1% (=1 g/l) 4.211, assuming all pairs of Cys residues form cystines
  Ext. coefficient 11000
  Abs 0.1% (=1 g/l) 4.163, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID Not available

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US20020086420A1

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DCTPep is developed by Dr.Zheng's team.