FSEN

General Information


DCTPep ID  DCTPep04839

Peptide Name   FSEN

Sequence  CQNHHAKHGKVC

Sequence Length  12

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C55H88N22O15S2

Absent amino acids  DEFILMPRSTWY

Theoretical pI  8.91

Acidic residues  0

Basic residues  5

Polar residues  4

Molecular weight (Average)  1361.56

Molecular weight (Monoisotopic)  1360.62

Common amino acids  H

Net charge  5

Instability index (II)  -19.91

Aliphatic index  32.50

Grand average of hydropathicity (GRAVY)  -1.150

Half Life 
  1.2 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 125
  Abs 0.1% (=1 g/l) 0.092, assuming all pairs of Cys residues form cystines
  Ext. coefficient 0
  Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 11311231

Title  A small peptide derived from Flt-1 (VEGFR-1) functions as an angiogenic inhibitor

Doi 10.1016/s0014-5793(01)02314-6

Year  2001

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DCTPep is developed by Dr.Zheng's team.