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cyclic decapeptide
General Information
DCTPep ID DCTPep04840
Peptide Name cyclic decapeptide
Sequence CTTHWGFTLC
Sequence Length 10
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Cys1<--->Cys10
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C52H73N13O14S2
Absent amino acids ADEIKMNPQRSVY
Theoretical pI 6.72
Acidic residues 0
Basic residues 1
Polar residues 6
Molecular weight (Average) 1168.35
Molecular weight (Monoisotopic) 1167.48
Common amino acids T
Net charge 1
Instability index (II) 28.35
Aliphatic index 39.00
Grand average of hydropathicity (GRAVY) 0.500
Half Life
1.2 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5625
Abs 0.1% (=1 g/l) 4.814, assuming all pairs of Cys residues form cystines
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 4.707, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 17121909
Title How molecular imaging is speeding up antiangiogenic drug development
Doi 10.1158/1535-7163.MCT-06-0395
Year 2006
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.