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TSP-1
General Information
DCTPep ID DCTPep04842
Peptide Name TSP-1
Sequence DDDDDNDKIPDDRDN
Sequence Length 15
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C67H101N21O36
Absent amino acids ACEFGHLMQSTVWY
Theoretical pI 3.62
Acidic residues 9
Basic residues 2
Polar residues 2
Molecular weight (Average) 1776.66
Molecular weight (Monoisotopic) 1775.67
Common amino acids D
Net charge -7
Instability index (II) -13.96
Aliphatic index 26.00
Grand average of hydropathicity (GRAVY) -2.933
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 20056600
Title Non-peptidic thrombospondin-1 mimics as fibroblast growth factor-2 inhibitors: an integrated strategy for the development of new antiangiogenic compounds
Year 2010
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.