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C16Y
General Information
DCTPep ID DCTPep04845
Peptide Name C16Y
Sequence DFKLFAVYIKYR
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Laminin
Type Synthetic peptide
Classification
Cancer targeted peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target αvβ3, α5β1
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C78H115N17O17
Absent amino acids CEGHMNPQSTW
Theoretical pI 9.53
Acidic residues 1
Basic residues 3
Polar residues 2
Molecular weight (Average) 1562.87
Molecular weight (Monoisotopic) 1561.87
Common amino acids FKY
Net charge 2
Instability index (II) -44.17
Aliphatic index 97.50
Grand average of hydropathicity (GRAVY) 0.125
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 2980
Abs 0.1% (=1 g/l) 1.907
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 21470139
Title Anti-angiogenic peptides for cancer therapeutics
Doi 10.2174/138920111796117300
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.