Loop 6
General Information
DCTPep ID DCTPep04854
Peptide Name Loop 6
Sequence ECLWMDWVTEKNINGHQAKFFACI
Sequence Length 24
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Cyclic
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C131H191N33O35S3
Absent amino acids PRSY
Theoretical pI 5.45
Acidic residues 3
Basic residues 3
Polar residues 6
Molecular weight (Average) 2884.34
Molecular weight (Monoisotopic) 2882.33
Common amino acids ACEFIKNW
Net charge 0
Instability index (II) 86.95
Aliphatic index 69.17
Grand average of hydropathicity (GRAVY) -0.075
Half Life
1 hours (mammalian reticulocytes, in vitro).
30 min (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 11125
Abs 0.1% (=1 g/l) 3.857, assuming all pairs of Cys residues form cystines
Ext. coefficient 11000
Abs 0.1% (=1 g/l) 3.814, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US8431396B2
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available