This work is licensed under a Creative Commons Attribution 4.0 International License.
hsurvivin
General Information
DCTPep ID DCTPep04865
Peptide Name hsurvivin
Sequence FLKDHRISTFKNWPF
Sequence Length 15
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C94H134N24O21
Absent amino acids ACEGMQVY
Theoretical pI 9.99
Acidic residues 1
Basic residues 4
Polar residues 3
Molecular weight (Average) 1936.25
Molecular weight (Monoisotopic) 1935.02
Common amino acids F
Net charge 3
Instability index (II) 7.81
Aliphatic index 52.00
Grand average of hydropathicity (GRAVY) -0.653
Half Life
1.1 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 2.841
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 17142738
Title Dendritic cell targeting of survivin protein in a xenogeneic form elicits strong CD4+ T cell immunity to mouse survivin
Doi 10.4049/jimmunol.177.12.8410
Year 2006
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.