This work is licensed under a Creative Commons Attribution 4.0 International License.
VEGFderived peptide
General Information
DCTPep ID DCTPep04921
Peptide Name VEGFderived peptide
Sequence KSVRGKGKGQKRKRKKSRYK
Sequence Length 20
UniProt ID Not available
PubChem CID Not available
Origin Exon 6a of VEGF gene
Type Synthetic peptide
Classification
Cancer targeted peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target VEGFR2
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C103H191N41O25
Absent amino acids ACDEFHILMNPTW
Theoretical pI 12.04
Acidic residues 0
Basic residues 12
Polar residues 6
Molecular weight (Average) 2403.91
Molecular weight (Monoisotopic) 2402.49
Common amino acids K
Net charge 12
Instability index (II) 26.74
Aliphatic index 14.50
Grand average of hydropathicity (GRAVY) -2.630
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.620
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 21470139
Title Anti-angiogenic peptides for cancer therapeutics
Doi 10.2174/138920111796117300
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.