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Flt1-12
General Information
DCTPep ID DCTPep04972
Peptide Name Flt1-12
Sequence RPFVEMYSEIPE
Sequence Length 12
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C68H101N15O21S1
Absent amino acids ACDGHKLNQTW
Theoretical pI 4.25
Acidic residues 3
Basic residues 1
Polar residues 2
Molecular weight (Average) 1496.7
Molecular weight (Monoisotopic) 1495.7
Common amino acids E
Net charge -2
Instability index (II) 105.18
Aliphatic index 56.67
Grand average of hydropathicity (GRAVY) -0.575
Half Life
1 hours (mammalian reticulocytes, in vitro).
2 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.996
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 11311231
Title A small peptide derived from Flt-1 (VEGFR-1) functions as an angiogenic inhibitor
Doi 10.1016/s0014-5793(01)02314-6
Year 2001
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.