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P144
General Information
DCTPep ID DCTPep05019
Peptide Name P144
Sequence TSLDASIIWAMMQN
Sequence Length 14
UniProt ID Not available
PubChem CID Not available
Origin TGFβ Receptor
Type Synthetic peptide
Classification
Cancer targeted peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target TGFβ
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C68H109N17O22S2
Absent amino acids CEFGHKPRVY
Theoretical pI 3.80
Acidic residues 1
Basic residues 0
Polar residues 4
Molecular weight (Average) 1580.83
Molecular weight (Monoisotopic) 1579.74
Common amino acids AIMS
Net charge -1
Instability index (II) -8.89
Aliphatic index 97.86
Grand average of hydropathicity (GRAVY) 0.464
Half Life
7.2 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 3.479
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 21470139
Title Anti-angiogenic peptides for cancer therapeutics
Doi 10.2174/138920111796117300
Year 2011
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.