TL1AL72-L251(rev)

General Information


DCTPep ID  DCTPep05048

Peptide Name   TL1AL72-L251(rev)

Sequence  YRIPIVRRLQRR

Sequence Length  12

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Cancer therapy related peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C72H128N28O15

Absent amino acids  ACDEFGHKMNSTW

Theoretical pI  12.18

Acidic residues  0

Basic residues  5

Polar residues  1

Molecular weight (Average)  1625.99

Molecular weight (Monoisotopic)  1625.01

Common amino acids  R

Net charge  5

Instability index (II)  108.23

Aliphatic index  121.67

Grand average of hydropathicity (GRAVY)  -0.992

Half Life 
  2.8 hours (mammalian reticulocytes, in vitro).
  10 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 1490
  Abs 0.1% (=1 g/l) 0.916

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 20675618

Title  Two functionally distinct isoforms of TL1A (TNFSF15) generated by differential ectodomain shedding

Doi 10.1093/gerona/glq129

Year  2010

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DCTPep is developed by Dr.Zheng's team.