This work is licensed under a Creative Commons Attribution 4.0 International License.
TL1AV84-L251(fw)
General Information
DCTPep ID DCTPep05050
Peptide Name TL1AV84-L251(fw)
Sequence YTYGLCTSSR
Sequence Length 10
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer therapy related peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C49H75N13O17S1
Absent amino acids ADEFHIKMNPQVW
Theoretical pI 8.20
Acidic residues 0
Basic residues 1
Polar residues 8
Molecular weight (Average) 1150.27
Molecular weight (Monoisotopic) 1149.51
Common amino acids STY
Net charge 1
Instability index (II) 63.14
Aliphatic index 39.00
Grand average of hydropathicity (GRAVY) -0.420
Half Life
2.8 hours (mammalian reticulocytes, in vitro).
10 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 2980
Abs 0.1% (=1 g/l) 2.591, assuming all pairs of Cys residues form cystines
Ext. coefficient 2980
Abs 0.1% (=1 g/l) 2.591, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 20675618
Title Two functionally distinct isoforms of TL1A (TNFSF15) generated by differential ectodomain shedding
Year 2010
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
This work is licensed under a Creative Commons Attribution 4.0 International License.