This work is licensed under a Creative Commons Attribution 4.0 International License.
Tat (43-60)
General Information
DCTPep ID DCTPep05051
Peptide Name Tat (43-60)
Sequence LGISYGRKKRRQRRRPPQ
Sequence Length 18
UniProt ID Not available
PubChem CID Not available
Origin Protein derived
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HeLa
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Labelled with Cys-acetamidomethyl
C-terminal Modification Fluorescein maleimide
Other Modification None
Chiral L
Physicochemical Information
Formula C96H170N40O23
Absent amino acids ACDEFHMNTVW
Theoretical pI 12.31
Acidic residues 0
Basic residues 8
Polar residues 4
Molecular weight (Average) 2252.66
Molecular weight (Monoisotopic) 2251.34
Common amino acids R
Net charge 8
Instability index (II) 156.39
Aliphatic index 43.33
Grand average of hydropathicity (GRAVY) -2.200
Half Life
5.5 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 1490
Abs 0.1% (=1 g/l) 0.661
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 9188504
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US6740524B1
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1002
This work is licensed under a Creative Commons Attribution 4.0 International License.