Retro - Tat (57-49)

General Information


DCTPep ID  DCTPep05059

Peptide Name   Retro - Tat (57-49)

Sequence  RRRQRRKKR

Sequence Length  9

UniProt ID  Not available

PubChem CID  Not available

Origin  Protein derived

Type  Native peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Penetrating Jurkat



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  fluorescein with 6-aminohexanoic acid (Ahx) spacer

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C53H106N30O11

Absent amino acids  ACDEFGHILMNPSTVWY

Theoretical pI  12.70

Acidic residues  0

Basic residues  8

Polar residues  0

Molecular weight (Average)  1339.62

Molecular weight (Monoisotopic)  1338.87

Common amino acids  R

Net charge  8

Instability index (II)  257.44

Aliphatic index  0.00

Grand average of hydropathicity (GRAVY)  -4.256

Half Life 
  1 hours (mammalian reticulocytes, in vitro).
  2 min (yeast, in vivo).
  2 min (Escherichia coli, in vivo).

Extinction coefficients 
  Should not be visible by UV spectrophotometry.

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 11087855

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID US6593292B1

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  1012

DCTPep is developed by Dr.Zheng's team.