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Ala substitution mutant of Tat (48-60)
General Information
DCTPep ID DCTPep05074
Peptide Name Ala substitution mutant of Tat (48-60)
Sequence GRKKRRQRARPPQC
Sequence Length 14
UniProt ID Not available
PubChem CID Not available
Origin Protein derived
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HeLa
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Fluorescein
Other Modification None
Chiral L
Physicochemical Information
Formula C70H129N33O17S1
Absent amino acids DEFHILMNSTVWY
Theoretical pI 12.18
Acidic residues 0
Basic residues 7
Polar residues 2
Molecular weight (Average) 1737.07
Molecular weight (Monoisotopic) 1736
Common amino acids R
Net charge 7
Instability index (II) 123.13
Aliphatic index 7.14
Grand average of hydropathicity (GRAVY) -2.614
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all pairs of Cys residues form cystines
Ext. coefficient 0
Abs 0.1% (=1 g/l) 0.000, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID Not available
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1027
This work is licensed under a Creative Commons Attribution 4.0 International License.