This work is licensed under a Creative Commons Attribution 4.0 International License.
Ala58 substitution mutant of pAntp (43-58)
General Information
DCTPep ID DCTPep05111
Peptide Name Ala58 substitution mutant of pAntp (43-58)
Sequence RQIKIWFQNRRMKWKA
Sequence Length 16
UniProt ID Not available
PubChem CID Not available
Origin Protein derived
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HaCat/ A549 cells
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Biotinylation (Labeled with Biotinyl-beta-Alanine)
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C101H161N33O20S1
Absent amino acids CDEGHLPSTVY
Theoretical pI 12.31
Acidic residues 0
Basic residues 6
Polar residues 1
Molecular weight (Average) 2189.66
Molecular weight (Monoisotopic) 2188.23
Common amino acids KR
Net charge 6
Instability index (II) 46.6
Aliphatic index 55.00
Grand average of hydropathicity (GRAVY) -1.375
Half Life
1 hours (mammalian reticulocytes, in vitro).
2 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 11000
Abs 0.1% (=1 g/l) 5.024
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 10784032
Title Not available
Doi Not available
Year Not available
Patent
Patent ID US7153931B1
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1130
This work is licensed under a Creative Commons Attribution 4.0 International License.