Reduced linear penetratin

General Information


DCTPep ID  DCTPep05112

Peptide Name   Reduced linear penetratin

Sequence  CRQIKIWFPNRRMKWKKC

Sequence Length  18

UniProt ID  Not available

PubChem CID  45029001 

Origin  Protein derived

Type  Native peptide

Classification

  

Cancer targeted peptides Membrane-targeted Cell-penetrating peptides



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Penetrating HaCat/ A549 cells



Structure Information


PDB ID  Not available

Predicted Structure  Not available

(Please note that there is the predicted structure, predicted by AlphaFold)

SequenceNo structure available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Biotinylation (Labeled with Biotinyl-Ahx)

C-terminal Modification  Unknown

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C110H177N35O21S3

Absent amino acids  ADEGHLSTVY

Theoretical pI  11.08

Acidic residues  0

Basic residues  7

Polar residues  3

Molecular weight (Average)  2422.02

Molecular weight (Monoisotopic)  2420.3

Common amino acids  K

Net charge  7

Instability index (II)  53.23

Aliphatic index  43.33

Grand average of hydropathicity (GRAVY)  -1.156

Half Life 
  1.2 hours (mammalian reticulocytes, in vitro).
  >20 hours (yeast, in vivo).
  >10 hours (Escherichia coli, in vivo).

Extinction coefficients 
  Ext. coefficient 11125
  Abs 0.1% (=1 g/l) 4.593, assuming all pairs of Cys residues form cystines
  Ext. coefficient 11000
  Abs 0.1% (=1 g/l) 4.542, assuming all Cys residues are reduced

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 10784032

Title  Not available

Doi Not available

Year  Not available

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




Cppsite ID  1131

DCTPep is developed by Dr.Zheng's team.