This work is licensed under a Creative Commons Attribution 4.0 International License.
DPV6
General Information
DCTPep ID DCTPep05115
Peptide Name DPV6
Sequence GRPRESGKKRKRKRLKP
Sequence Length 17
UniProt ID Not available
PubChem CID Not available
Origin Protein derived
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HeLa, HCT116, HL-60, K562, Molt4, NIH-3T3 and primary hepatocyte cultures
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Cys addition
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C88H165N37O21
Absent amino acids ACDFHIMNQTVWY
Theoretical pI 12.19
Acidic residues 1
Basic residues 10
Polar residues 3
Molecular weight (Average) 2077.51
Molecular weight (Monoisotopic) 2076.3
Common amino acids KR
Net charge 9
Instability index (II) 70.74
Aliphatic index 22.94
Grand average of hydropathicity (GRAVY) -2.735
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Should not be visible by UV spectrophotometry.
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 15859953
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1207
This work is licensed under a Creative Commons Attribution 4.0 International License.