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No. 2028
General Information
DCTPep ID DCTPep05148
Peptide Name No. 2028
Sequence KNAWKHSSCHHRHQI
Sequence Length 15
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HeLa, Jurkat and CHO
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Carboxyfluorescein
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C80H121N31O20S1
Absent amino acids DEFGLMPTVY
Theoretical pI 10.06
Acidic residues 0
Basic residues 7
Polar residues 4
Molecular weight (Average) 1869.1
Molecular weight (Monoisotopic) 1867.91
Common amino acids H
Net charge 7
Instability index (II) 78.48
Aliphatic index 32.67
Grand average of hydropathicity (GRAVY) -1.720
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 2.943, assuming all pairs of Cys residues form cystines
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 2.943, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 19956900
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1267
This work is licensed under a Creative Commons Attribution 4.0 International License.