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LAMBDA N (1-22)
General Information
DCTPep ID DCTPep05160
Peptide Name LAMBDA N (1-22)
Sequence MDAQTRRRERRAEKQAQWKAANGC
Sequence Length 24
UniProt ID Not available
PubChem CID Not available
Origin Protein derived
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating RAW 264.7
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Conjugation with fluorescein by C-terminal Gly Cys amide
Other Modification None
Chiral L
Physicochemical Information
Formula C115H194N46O36S2
Absent amino acids FHILPSVY
Theoretical pI 10.79
Acidic residues 3
Basic residues 7
Polar residues 4
Molecular weight (Average) 2861.21
Molecular weight (Monoisotopic) 2859.42
Common amino acids AR
Net charge 4
Instability index (II) 84.79
Aliphatic index 20.83
Grand average of hydropathicity (GRAVY) -1.808
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 1.922, assuming all pairs of Cys residues form cystines
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 1.922, assuming all Cys residues are reduced
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 11084031
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1401
This work is licensed under a Creative Commons Attribution 4.0 International License.