This work is licensed under a Creative Commons Attribution 4.0 International License.
Pep-3
General Information
DCTPep ID DCTPep05168
Peptide Name Pep-3
Sequence KWFETWFTEWPKKRK
Sequence Length 15
UniProt ID Not available
PubChem CID Not available
Origin Chimeric
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HeLa
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Acetylation
C-terminal Modification Cysteamide
Other Modification None
Chiral L
Physicochemical Information
Formula C104H145N25O22
Absent amino acids ACDGHILMNQSVY
Theoretical pI 10.00
Acidic residues 2
Basic residues 5
Polar residues 2
Molecular weight (Average) 2097.45
Molecular weight (Monoisotopic) 2096.1
Common amino acids K
Net charge 3
Instability index (II) 23.87
Aliphatic index 0.00
Grand average of hydropathicity (GRAVY) -1.813
Half Life
1.3 hours (mammalian reticulocytes, in vitro).
3 min (yeast, in vivo).
3 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 16500
Abs 0.1% (=1 g/l) 7.867
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 20188697
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1419
This work is licensed under a Creative Commons Attribution 4.0 International License.