This work is licensed under a Creative Commons Attribution 4.0 International License.
MPG Mutant
General Information
DCTPep ID DCTPep05170
Peptide Name MPG Mutant
Sequence GALFLGFLGAAGSTMGAWSQPKSKRKV
Sequence Length 27
UniProt ID Not available
PubChem CID Not available
Origin Chimeric
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HS-68, Cos-7 and HeLa
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Acetylation
C-terminal Modification Cysteamide group
Other Modification None
Chiral L
Physicochemical Information
Formula C126H201N35O33S1
Absent amino acids CDEHINY
Theoretical pI 11.26
Acidic residues 0
Basic residues 4
Polar residues 9
Molecular weight (Average) 2766.26
Molecular weight (Monoisotopic) 2764.48
Common amino acids G
Net charge 4
Instability index (II) 23.39
Aliphatic index 68.89
Grand average of hydropathicity (GRAVY) 0.111
Half Life
30 hours (mammalian reticulocytes, in vitro).
>20 hours (yeast, in vivo).
>10 hours (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 5500
Abs 0.1% (=1 g/l) 1.988
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 12771197
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1424
This work is licensed under a Creative Commons Attribution 4.0 International License.