This work is licensed under a Creative Commons Attribution 4.0 International License.
PDX -1-PTD
General Information
DCTPep ID DCTPep05196
Peptide Name PDX -1-PTD
Sequence RHIKIWFQNRRMKWKK
Sequence Length 16
UniProt ID Not available
PubChem CID Not available
Origin Protein derived
Type Native peptide
Classification
Cancer targeted peptides Membrane-targeted Cell-penetrating peptides
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Penetrating HeLa, HepG2, MIN6 and islets cells
Structure Information
PDB ID Not available
Predicted Structure Not available
(Please note that there is the predicted structure, predicted by AlphaFold)
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification FITC
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C105H167N35O19S1
Absent amino acids ACDEGLPSTVY
Theoretical pI 12.31
Acidic residues 0
Basic residues 8
Polar residues 1
Molecular weight (Average) 2255.76
Molecular weight (Monoisotopic) 2254.29
Common amino acids K
Net charge 8
Instability index (II) 74.06
Aliphatic index 48.75
Grand average of hydropathicity (GRAVY) -1.712
Half Life
1 hours (mammalian reticulocytes, in vitro).
2 min (yeast, in vivo).
2 min (Escherichia coli, in vivo).
Extinction coefficients
Ext. coefficient 11000
Abs 0.1% (=1 g/l) 4.876
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 12829640
Title Not available
Doi Not available
Year Not available
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
Cppsite ID 1495
This work is licensed under a Creative Commons Attribution 4.0 International License.